{"id":170,"date":"2019-10-17T19:31:13","date_gmt":"2019-10-17T19:31:13","guid":{"rendered":"https:\/\/pressbooks.publishdot.com\/nursingpharmacology\/chapter\/4-6-muscarinic-receptor-agonist\/"},"modified":"2021-12-07T11:10:38","modified_gmt":"2021-12-07T11:10:38","slug":"4-6-muscarinic-receptor-agonist","status":"publish","type":"chapter","link":"https:\/\/pressbooks.publishdot.com\/nursingpharmacology\/chapter\/4-6-muscarinic-receptor-agonist\/","title":{"raw":"4.6 Muscarinic Receptor Agonists","rendered":"4.6 Muscarinic Receptor Agonists"},"content":{"raw":"Pilocarpine is a muscarinic receptor agonist.\n\n<strong>Mechanism of Action:<\/strong> Pilocarpine causes the ciliary muscle to contract, allowing for the drainage of aqueous humor from the anterior chamber of the eye and reducing intraocular pressure related to glaucoma.\n\n<strong>Indication:<\/strong> Pilocarpine is used to treat glaucoma.\n\n<strong>Nursing Considerations:<\/strong> Remove contact lens before administration. Apply light finger pressure on lacrimal sac for 2 minutes after instilling to minimize systemic absorption.\n\n<strong>Patient Teaching &amp; Education:<\/strong>\u00a0 Advise the patient to use caution with night driving.\u00a0 Additionally, use of this medication can cause hypotension.<sup>[footnote]uCentral from Unbound Medicine. <a href=\"https:\/\/www.unboundmedicine.com\/ucentral\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/www.unboundmedicine.com\/ucentral<\/a>[\/footnote]<\/sup>\n\nNow let's take a closer look at the medication grid on pilocarpine in Table 4.6.<sup>[footnote]This work is a derivative of <a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/\" target=\"_blank\" rel=\"noopener noreferrer\">Daily Med<\/a> by <a href=\"https:\/\/www.nlm.nih.gov\/\" target=\"_blank\" rel=\"noopener noreferrer\">U.S. National Library of Medicine<\/a> in the <a href=\"https:\/\/creativecommons.org\/share-your-work\/public-domain\/\" target=\"_blank\" rel=\"noopener noreferrer\">public domain<\/a>.[\/footnote]<\/sup>\n\nTable 4.6 Pilocarpine Medication Grid\n<table class=\"grid\" border=\"0\">\n<tbody>\n<tr>\n<th style=\"width: 131.063px\" scope=\"col\">\n<h5><strong>Class\/Subclass<\/strong><\/h5>\n<\/th>\n<th style=\"width: 164.063px\" scope=\"col\">\n<h5><strong>Prototype\/Generic<\/strong><\/h5>\n<\/th>\n<th style=\"width: 384.063px\" scope=\"col\">\n<h5><strong>Administration Considerations<\/strong><\/h5>\n<\/th>\n<th style=\"width: 358.063px\" scope=\"col\">\n<h5><strong>Therapeutic Effects<\/strong><\/h5>\n<\/th>\n<th style=\"width: 263.063px\" scope=\"col\">\n<h5><strong>Side\/Adverse Effects<\/strong><\/h5>\n<\/th>\n<\/tr>\n<tr>\n<th style=\"width: 131.063px\" scope=\"row\">Muscarinic Agonist<\/th>\n<td style=\"width: 164.063px\"><a class=\"rId63\" href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=fa03947c-6844-45df-aa22-b584c5681269&amp;audience=consumer\" target=\"_blank\" rel=\"noopener noreferrer\"><strong>pilocarpine<\/strong><\/a><\/td>\n<td style=\"width: 384.063px\">Remove contact lens before administration\n\nApply light finger pressure on lacrimal sac for 2 minutes after instilling to minimize systemic absorption<\/td>\n<td style=\"width: 358.063px\">Controls intraocular pressure in glaucoma<\/td>\n<td style=\"width: 263.063px\">Caution with night driving<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n&nbsp;","rendered":"<p>Pilocarpine is a muscarinic receptor agonist.<\/p>\n<p><strong>Mechanism of Action:<\/strong> Pilocarpine causes the ciliary muscle to contract, allowing for the drainage of aqueous humor from the anterior chamber of the eye and reducing intraocular pressure related to glaucoma.<\/p>\n<p><strong>Indication:<\/strong> Pilocarpine is used to treat glaucoma.<\/p>\n<p><strong>Nursing Considerations:<\/strong> Remove contact lens before administration. Apply light finger pressure on lacrimal sac for 2 minutes after instilling to minimize systemic absorption.<\/p>\n<p><strong>Patient Teaching &amp; Education:<\/strong>\u00a0 Advise the patient to use caution with night driving.\u00a0 Additionally, use of this medication can cause hypotension.<sup><a class=\"footnote\" title=\"uCentral from Unbound Medicine. https:\/\/www.unboundmedicine.com\/ucentral\" id=\"return-footnote-170-1\" href=\"#footnote-170-1\" aria-label=\"Footnote 1\"><sup class=\"footnote\">[1]<\/sup><\/a><\/sup><\/p>\n<p>Now let&#8217;s take a closer look at the medication grid on pilocarpine in Table 4.6.<sup><a class=\"footnote\" title=\"This work is a derivative of Daily Med by U.S. National Library of Medicine in the public domain.\" id=\"return-footnote-170-2\" href=\"#footnote-170-2\" aria-label=\"Footnote 2\"><sup class=\"footnote\">[2]<\/sup><\/a><\/sup><\/p>\n<p>Table 4.6 Pilocarpine Medication Grid<\/p>\n<table class=\"grid\">\n<tbody>\n<tr>\n<th style=\"width: 131.063px\" scope=\"col\">\n<h5><strong>Class\/Subclass<\/strong><\/h5>\n<\/th>\n<th style=\"width: 164.063px\" scope=\"col\">\n<h5><strong>Prototype\/Generic<\/strong><\/h5>\n<\/th>\n<th style=\"width: 384.063px\" scope=\"col\">\n<h5><strong>Administration Considerations<\/strong><\/h5>\n<\/th>\n<th style=\"width: 358.063px\" scope=\"col\">\n<h5><strong>Therapeutic Effects<\/strong><\/h5>\n<\/th>\n<th style=\"width: 263.063px\" scope=\"col\">\n<h5><strong>Side\/Adverse Effects<\/strong><\/h5>\n<\/th>\n<\/tr>\n<tr>\n<th style=\"width: 131.063px\" scope=\"row\">Muscarinic Agonist<\/th>\n<td style=\"width: 164.063px\"><a class=\"rId63\" href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=fa03947c-6844-45df-aa22-b584c5681269&amp;audience=consumer\" target=\"_blank\" rel=\"noopener noreferrer\"><strong>pilocarpine<\/strong><\/a><\/td>\n<td style=\"width: 384.063px\">Remove contact lens before administration<\/p>\n<p>Apply light finger pressure on lacrimal sac for 2 minutes after instilling to minimize systemic absorption<\/td>\n<td style=\"width: 358.063px\">Controls intraocular pressure in glaucoma<\/td>\n<td style=\"width: 263.063px\">Caution with night driving<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<hr class=\"before-footnotes clear\" \/><div class=\"footnotes\"><ol><li id=\"footnote-170-1\">uCentral from Unbound Medicine. <a href=\"https:\/\/www.unboundmedicine.com\/ucentral\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/www.unboundmedicine.com\/ucentral<\/a> <a href=\"#return-footnote-170-1\" class=\"return-footnote\" aria-label=\"Return to footnote 1\">&crarr;<\/a><\/li><li id=\"footnote-170-2\">This work is a derivative of <a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/\" target=\"_blank\" rel=\"noopener noreferrer\">Daily Med<\/a> by <a href=\"https:\/\/www.nlm.nih.gov\/\" target=\"_blank\" rel=\"noopener noreferrer\">U.S. National Library of Medicine<\/a> in the <a href=\"https:\/\/creativecommons.org\/share-your-work\/public-domain\/\" target=\"_blank\" rel=\"noopener noreferrer\">public domain<\/a>. <a href=\"#return-footnote-170-2\" class=\"return-footnote\" aria-label=\"Return to footnote 2\">&crarr;<\/a><\/li><\/ol><\/div>","protected":false},"author":2,"menu_order":6,"template":"","meta":{"pb_show_title":"on","pb_short_title":"","pb_subtitle":"","pb_authors":[],"pb_section_license":"cc-by"},"chapter-type":[49],"contributor":[],"license":[53],"class_list":["post-170","chapter","type-chapter","status-publish","hentry","chapter-type-numberless","license-cc-by"],"part":149,"_links":{"self":[{"href":"https:\/\/pressbooks.publishdot.com\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapters\/170","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pressbooks.publishdot.com\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapters"}],"about":[{"href":"https:\/\/pressbooks.publishdot.com\/nursingpharmacology\/wp-json\/wp\/v2\/types\/chapter"}],"author":[{"embeddable":true,"href":"https:\/\/pressbooks.publishdot.com\/nursingpharmacology\/wp-json\/wp\/v2\/users\/2"}],"version-history":[{"count":1,"href":"https:\/\/pressbooks.publishdot.com\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapters\/170\/revisions"}],"predecessor-version":[{"id":171,"href":"https:\/\/pressbooks.publishdot.com\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapters\/170\/revisions\/171"}],"part":[{"href":"https:\/\/pressbooks.publishdot.com\/nursingpharmacology\/wp-json\/pressbooks\/v2\/parts\/149"}],"metadata":[{"href":"https:\/\/pressbooks.publishdot.com\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapters\/170\/metadata\/"}],"wp:attachment":[{"href":"https:\/\/pressbooks.publishdot.com\/nursingpharmacology\/wp-json\/wp\/v2\/media?parent=170"}],"wp:term":[{"taxonomy":"chapter-type","embeddable":true,"href":"https:\/\/pressbooks.publishdot.com\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapter-type?post=170"},{"taxonomy":"contributor","embeddable":true,"href":"https:\/\/pressbooks.publishdot.com\/nursingpharmacology\/wp-json\/wp\/v2\/contributor?post=170"},{"taxonomy":"license","embeddable":true,"href":"https:\/\/pressbooks.publishdot.com\/nursingpharmacology\/wp-json\/wp\/v2\/license?post=170"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}