{"id":218,"date":"2019-11-12T17:43:11","date_gmt":"2019-11-12T17:43:11","guid":{"rendered":"https:\/\/pressbooks.publishdot.com\/nursingpharmacology\/chapter\/5-7-decongestants\/"},"modified":"2021-12-07T11:11:13","modified_gmt":"2021-12-07T11:11:13","slug":"5-7-decongestants","status":"publish","type":"chapter","link":"https:\/\/pressbooks.publishdot.com\/nursingpharmacology\/chapter\/5-7-decongestants\/","title":{"raw":"5.7 Decongestants","rendered":"5.7 Decongestants"},"content":{"raw":"[caption id=\"attachment_217\" align=\"alignright\" width=\"596\"]<img class=\"wp-image-217\" title=\"&quot;Project 366 #165: 130612 Helping Hand?&quot; by Pete is licensed under CC0 1.0\" src=\"https:\/\/pressbooks.publishdot.com\/nursingpharmacology\/wp-content\/uploads\/sites\/5\/2019\/11\/image7-7-1024x682.png\" alt=\"Photo of Sudafed package\" width=\"596\" height=\"397\"> Figure 5.9 Pseudoephedrine (Sudafed) is a decongestant that is available OTC[\/caption]\n\nPseudoephedrine is an over-the-counter (OTC) decongestant (see Figure 5.9<sup>[footnote]\"<a href=\"https:\/\/www.flickr.com\/photos\/comedynose\/7184518521\" target=\"_blank\" rel=\"noopener noreferrer\">Project 366 #165: 130612 Helping Hand?<\/a>\" by <a href=\"https:\/\/www.flickr.com\/photos\/comedynose\/\" target=\"_blank\" rel=\"noopener noreferrer\">Pete<\/a> is licensed under <a href=\"https:\/\/creativecommons.org\/publicdomain\/mark\/1.0\/\" target=\"_blank\" rel=\"noopener noreferrer\">public domain<\/a>[\/footnote]<\/sup>).\u00a0 More details regarding pseudoephedrine are described in the \"Autonomic Nervous System\" chapter.\n\n<strong>Mechanism of Action<\/strong>\n\nPseudoephedrine acts directly on the adrenergic receptors and acts indirectly by releasing norepinephrine from its storage sites. The drug produces vasoconstriction, which shrinks nasal mucosa membranes.\n\n<strong>Indications for Use<\/strong>\n\nDecongestants relieve nasal obstruction due to inflammation.\n\n<strong>Nursing Considerations Across the Lifespan<\/strong>\n\nThis medication is not safe for children under the age of 4 years.\n\n<strong>Adverse\/Side Effects<\/strong>\n\nCommon adverse\/side effects include hypertension, dysrhythmia, dizziness, headache, insomnia, and restlessness. Some patients may experience blurred vision, tinnitus, chest tightness, dry nose, and nasal congestion.\n\nDecongestants are contraindicated in patients with severe hypertension, coronary artery disease (CAD), narrow-angle glaucoma, and some antidepressant use. Also, use with caution in patients who have cardiac dysrhythmias, hyperthyroidism, DM (diabetes mellitus), prostatic hypertrophy, and glaucoma.<sup>[footnote]Frandsen, G. &amp; Pennington, S. (2018). <em>Abrams\u2019 clinical drug: Rationales for nursing practice <\/em>(11th ed.). Wolters Kluwer.[\/footnote]<\/sup>\n\n<strong>Patient Teaching &amp; Education<\/strong>\n\nPatients must take care to follow dosing recommendations.\u00a0 If dosing standards are surpassed, some patients may experience side effects such as increased nervousness, breathing difficulties, heart rate changes, and hallucinations.<sup>[footnote]uCentral from Unbound Medicine. <a href=\"https:\/\/www.unboundmedicine.com\/ucentral\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/www.unboundmedicine.com\/ucentral<\/a>[\/footnote]<\/sup>\n\nNow let's take a closer look at the medication grid on Pseudoephedrine in Table 5.7.<span style=\"text-align: initial;font-size: 1em\"><sup>[footnote]This work is a derivative of\u00a0<a href=\"https:\/\/www.oercommons.org\/authoring\/54330-pharmacology-notes-nursing-implications-for-clinic\/view\" target=\"_blank\" rel=\"noopener noreferrer\">Pharmacology Notes: Nursing Implications for Clinical Practice<\/a>\u00a0by\u00a0<a href=\"https:\/\/www.oercommons.org\/profile\/213497\" target=\"_blank\" rel=\"noopener noreferrer\">Gloria Velarde<\/a>\u00a0is licensed under\u00a0<a href=\"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0\/\" target=\"_blank\" rel=\"noopener noreferrer\">CC BY-NC-SA 4.0<\/a>.[\/footnote], [footnote]Frandsen, G. &amp; Pennington, S. (2018).\u00a0<em>Abrams\u2019 clinical drug: Rationales for nursing practice\u00a0<\/em>(11th ed.). Wolters Kluwer.[\/footnote], [footnote]This work is a derivative of\u00a0<a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/\" target=\"_blank\" rel=\"noopener noreferrer\">Daily Med<\/a>\u00a0by\u00a0<a href=\"https:\/\/www.nlm.nih.gov\/\" target=\"_blank\" rel=\"noopener noreferrer\">U.S. National Library of Medicine<\/a><span style=\"font-size: 1em\">\u00a0in the <a href=\"https:\/\/creativecommons.org\/share-your-work\/public-domain\/\" target=\"_blank\" rel=\"noopener noreferrer\">public domain<\/a>. [\/footnote]<\/span><\/sup><\/span>\n\nTable 5.7<span style=\"text-align: initial;font-size: 1em\"> Pseudoephedrine Medication Grid<\/span>\n<table class=\"grid\" border=\"0\">\n<tbody>\n<tr>\n<th style=\"width: 133.063px\" scope=\"col\">\n<h5><strong>Class\/Subclass<\/strong><\/h5>\n<\/th>\n<th style=\"width: 166.063px\" scope=\"col\">\n<h5><strong>Prototype\/Generic<\/strong><\/h5>\n<\/th>\n<th style=\"width: 361.063px\" scope=\"col\">\n<h5><strong>Administration Considerations<\/strong><\/h5>\n<\/th>\n<th style=\"width: 435.063px\" scope=\"col\">\n<h5><strong>Therapeutic Effects<\/strong><\/h5>\n<\/th>\n<th style=\"width: 205.063px\" scope=\"col\">\n<h5><strong>Adverse\/Side Effects<\/strong><\/h5>\n<\/th>\n<\/tr>\n<tr>\n<th style=\"width: 133.063px\" scope=\"row\">Decongestant<\/th>\n<td style=\"width: 166.063px\"><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=5e5f0b4b-c7ef-4372-a48c-b19728b14c59\" target=\"_blank\" rel=\"noopener noreferrer\">pseudoephedrine<\/a><\/td>\n<td style=\"width: 361.063px\">Administration (drops, sprays)\n\nAvoid prolonged use &gt; 7 days\n\nUse cautiously with cardiovascular disease\n\nMaintain hydration (2-3 liters\/day)<\/td>\n<td style=\"width: 435.063px\">Temporarily relieves nasal congestion due to the common cold, hay fever, or other upper respiratory allergies\n\nTemporarily relieves sinus congestion and pressure<\/td>\n<td style=\"width: 205.063px\">Cardiovascular\u00a0stimulation\n\nRebound congestion with nasal route<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n&nbsp;","rendered":"<figure id=\"attachment_217\" aria-describedby=\"caption-attachment-217\" style=\"width: 596px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-217\" title=\"&quot;Project 366 #165: 130612 Helping Hand?&quot; by Pete is licensed under CC0 1.0\" src=\"https:\/\/pressbooks.publishdot.com\/nursingpharmacology\/wp-content\/uploads\/sites\/5\/2019\/11\/image7-7-1024x682.png\" alt=\"Photo of Sudafed package\" width=\"596\" height=\"397\" \/><figcaption id=\"caption-attachment-217\" class=\"wp-caption-text\">Figure 5.9 Pseudoephedrine (Sudafed) is a decongestant that is available OTC<\/figcaption><\/figure>\n<p>Pseudoephedrine is an over-the-counter (OTC) decongestant (see Figure 5.9<sup><a class=\"footnote\" title=\"&quot;Project 366 #165: 130612 Helping Hand?&quot; by Pete is licensed under public domain\" id=\"return-footnote-218-1\" href=\"#footnote-218-1\" aria-label=\"Footnote 1\"><sup class=\"footnote\">[1]<\/sup><\/a><\/sup>).\u00a0 More details regarding pseudoephedrine are described in the &#8220;Autonomic Nervous System&#8221; chapter.<\/p>\n<p><strong>Mechanism of Action<\/strong><\/p>\n<p>Pseudoephedrine acts directly on the adrenergic receptors and acts indirectly by releasing norepinephrine from its storage sites. The drug produces vasoconstriction, which shrinks nasal mucosa membranes.<\/p>\n<p><strong>Indications for Use<\/strong><\/p>\n<p>Decongestants relieve nasal obstruction due to inflammation.<\/p>\n<p><strong>Nursing Considerations Across the Lifespan<\/strong><\/p>\n<p>This medication is not safe for children under the age of 4 years.<\/p>\n<p><strong>Adverse\/Side Effects<\/strong><\/p>\n<p>Common adverse\/side effects include hypertension, dysrhythmia, dizziness, headache, insomnia, and restlessness. Some patients may experience blurred vision, tinnitus, chest tightness, dry nose, and nasal congestion.<\/p>\n<p>Decongestants are contraindicated in patients with severe hypertension, coronary artery disease (CAD), narrow-angle glaucoma, and some antidepressant use. Also, use with caution in patients who have cardiac dysrhythmias, hyperthyroidism, DM (diabetes mellitus), prostatic hypertrophy, and glaucoma.<sup><a class=\"footnote\" title=\"Frandsen, G. &amp; Pennington, S. (2018). Abrams\u2019 clinical drug: Rationales for nursing practice (11th ed.). Wolters Kluwer.\" id=\"return-footnote-218-2\" href=\"#footnote-218-2\" aria-label=\"Footnote 2\"><sup class=\"footnote\">[2]<\/sup><\/a><\/sup><\/p>\n<p><strong>Patient Teaching &amp; Education<\/strong><\/p>\n<p>Patients must take care to follow dosing recommendations.\u00a0 If dosing standards are surpassed, some patients may experience side effects such as increased nervousness, breathing difficulties, heart rate changes, and hallucinations.<sup><a class=\"footnote\" title=\"uCentral from Unbound Medicine. https:\/\/www.unboundmedicine.com\/ucentral\" id=\"return-footnote-218-3\" href=\"#footnote-218-3\" aria-label=\"Footnote 3\"><sup class=\"footnote\">[3]<\/sup><\/a><\/sup><\/p>\n<p>Now let&#8217;s take a closer look at the medication grid on Pseudoephedrine in Table 5.7.<span style=\"text-align: initial;font-size: 1em\"><sup><a class=\"footnote\" title=\"This work is a derivative of\u00a0Pharmacology Notes: Nursing Implications for Clinical Practice\u00a0by\u00a0Gloria Velarde\u00a0is licensed under\u00a0CC BY-NC-SA 4.0.\" id=\"return-footnote-218-4\" href=\"#footnote-218-4\" aria-label=\"Footnote 4\"><sup class=\"footnote\">[4]<\/sup><\/a>, <a class=\"footnote\" title=\"Frandsen, G. &amp; Pennington, S. (2018).\u00a0Abrams\u2019 clinical drug: Rationales for nursing practice\u00a0(11th ed.). Wolters Kluwer.\" id=\"return-footnote-218-5\" href=\"#footnote-218-5\" aria-label=\"Footnote 5\"><sup class=\"footnote\">[5]<\/sup><\/a>, <a class=\"footnote\" title=\"This work is a derivative of\u00a0Daily Med\u00a0by\u00a0U.S. National Library of Medicine\u00a0in the public domain.\" id=\"return-footnote-218-6\" href=\"#footnote-218-6\" aria-label=\"Footnote 6\"><sup class=\"footnote\">[6]<\/sup><\/a><\/span><\/sup><\/span><\/p>\n<p>Table 5.7<span style=\"text-align: initial;font-size: 1em\"> Pseudoephedrine Medication Grid<\/span><\/p>\n<table class=\"grid\">\n<tbody>\n<tr>\n<th style=\"width: 133.063px\" scope=\"col\">\n<h5><strong>Class\/Subclass<\/strong><\/h5>\n<\/th>\n<th style=\"width: 166.063px\" scope=\"col\">\n<h5><strong>Prototype\/Generic<\/strong><\/h5>\n<\/th>\n<th style=\"width: 361.063px\" scope=\"col\">\n<h5><strong>Administration Considerations<\/strong><\/h5>\n<\/th>\n<th style=\"width: 435.063px\" scope=\"col\">\n<h5><strong>Therapeutic Effects<\/strong><\/h5>\n<\/th>\n<th style=\"width: 205.063px\" scope=\"col\">\n<h5><strong>Adverse\/Side Effects<\/strong><\/h5>\n<\/th>\n<\/tr>\n<tr>\n<th style=\"width: 133.063px\" scope=\"row\">Decongestant<\/th>\n<td style=\"width: 166.063px\"><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=5e5f0b4b-c7ef-4372-a48c-b19728b14c59\" target=\"_blank\" rel=\"noopener noreferrer\">pseudoephedrine<\/a><\/td>\n<td style=\"width: 361.063px\">Administration (drops, sprays)<\/p>\n<p>Avoid prolonged use &gt; 7 days<\/p>\n<p>Use cautiously with cardiovascular disease<\/p>\n<p>Maintain hydration (2-3 liters\/day)<\/td>\n<td style=\"width: 435.063px\">Temporarily relieves nasal congestion due to the common cold, hay fever, or other upper respiratory allergies<\/p>\n<p>Temporarily relieves sinus congestion and pressure<\/td>\n<td style=\"width: 205.063px\">Cardiovascular\u00a0stimulation<\/p>\n<p>Rebound congestion with nasal route<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<hr class=\"before-footnotes clear\" \/><div class=\"footnotes\"><ol><li id=\"footnote-218-1\">\"<a href=\"https:\/\/www.flickr.com\/photos\/comedynose\/7184518521\" target=\"_blank\" rel=\"noopener noreferrer\">Project 366 #165: 130612 Helping Hand?<\/a>\" by <a href=\"https:\/\/www.flickr.com\/photos\/comedynose\/\" target=\"_blank\" rel=\"noopener noreferrer\">Pete<\/a> is licensed under <a href=\"https:\/\/creativecommons.org\/publicdomain\/mark\/1.0\/\" target=\"_blank\" rel=\"noopener noreferrer\">public domain<\/a> <a href=\"#return-footnote-218-1\" class=\"return-footnote\" aria-label=\"Return to footnote 1\">&crarr;<\/a><\/li><li id=\"footnote-218-2\">Frandsen, G. &amp; Pennington, S. (2018). <em>Abrams\u2019 clinical drug: Rationales for nursing practice <\/em>(11th ed.). Wolters Kluwer. <a href=\"#return-footnote-218-2\" class=\"return-footnote\" aria-label=\"Return to footnote 2\">&crarr;<\/a><\/li><li id=\"footnote-218-3\">uCentral from Unbound Medicine. <a href=\"https:\/\/www.unboundmedicine.com\/ucentral\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/www.unboundmedicine.com\/ucentral<\/a> <a href=\"#return-footnote-218-3\" class=\"return-footnote\" aria-label=\"Return to footnote 3\">&crarr;<\/a><\/li><li id=\"footnote-218-4\">This work is a derivative of\u00a0<a href=\"https:\/\/www.oercommons.org\/authoring\/54330-pharmacology-notes-nursing-implications-for-clinic\/view\" target=\"_blank\" rel=\"noopener noreferrer\">Pharmacology Notes: Nursing Implications for Clinical Practice<\/a>\u00a0by\u00a0<a href=\"https:\/\/www.oercommons.org\/profile\/213497\" target=\"_blank\" rel=\"noopener noreferrer\">Gloria Velarde<\/a>\u00a0is licensed under\u00a0<a href=\"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0\/\" target=\"_blank\" rel=\"noopener noreferrer\">CC BY-NC-SA 4.0<\/a>. <a href=\"#return-footnote-218-4\" class=\"return-footnote\" aria-label=\"Return to footnote 4\">&crarr;<\/a><\/li><li id=\"footnote-218-5\">Frandsen, G. &amp; Pennington, S. (2018).\u00a0<em>Abrams\u2019 clinical drug: Rationales for nursing practice\u00a0<\/em>(11th ed.). Wolters Kluwer. <a href=\"#return-footnote-218-5\" class=\"return-footnote\" aria-label=\"Return to footnote 5\">&crarr;<\/a><\/li><li id=\"footnote-218-6\">This work is a derivative of\u00a0<a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/\" target=\"_blank\" rel=\"noopener noreferrer\">Daily Med<\/a>\u00a0by\u00a0<a href=\"https:\/\/www.nlm.nih.gov\/\" target=\"_blank\" rel=\"noopener noreferrer\">U.S. National Library of Medicine<\/a><span style=\"font-size: 1em\">\u00a0in the <a href=\"https:\/\/creativecommons.org\/share-your-work\/public-domain\/\" target=\"_blank\" rel=\"noopener noreferrer\">public domain<\/a>.  <a href=\"#return-footnote-218-6\" class=\"return-footnote\" aria-label=\"Return to footnote 6\">&crarr;<\/a><\/li><\/ol><\/div>","protected":false},"author":2,"menu_order":7,"template":"","meta":{"pb_show_title":"on","pb_short_title":"","pb_subtitle":"","pb_authors":[],"pb_section_license":"cc-by"},"chapter-type":[49],"contributor":[],"license":[53],"class_list":["post-218","chapter","type-chapter","status-publish","hentry","chapter-type-numberless","license-cc-by"],"part":195,"_links":{"self":[{"href":"https:\/\/pressbooks.publishdot.com\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapters\/218","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pressbooks.publishdot.com\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapters"}],"about":[{"href":"https:\/\/pressbooks.publishdot.com\/nursingpharmacology\/wp-json\/wp\/v2\/types\/chapter"}],"author":[{"embeddable":true,"href":"https:\/\/pressbooks.publishdot.com\/nursingpharmacology\/wp-json\/wp\/v2\/users\/2"}],"version-history":[{"count":1,"href":"https:\/\/pressbooks.publishdot.com\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapters\/218\/revisions"}],"predecessor-version":[{"id":219,"href":"https:\/\/pressbooks.publishdot.com\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapters\/218\/revisions\/219"}],"part":[{"href":"https:\/\/pressbooks.publishdot.com\/nursingpharmacology\/wp-json\/pressbooks\/v2\/parts\/195"}],"metadata":[{"href":"https:\/\/pressbooks.publishdot.com\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapters\/218\/metadata\/"}],"wp:attachment":[{"href":"https:\/\/pressbooks.publishdot.com\/nursingpharmacology\/wp-json\/wp\/v2\/media?parent=218"}],"wp:term":[{"taxonomy":"chapter-type","embeddable":true,"href":"https:\/\/pressbooks.publishdot.com\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapter-type?post=218"},{"taxonomy":"contributor","embeddable":true,"href":"https:\/\/pressbooks.publishdot.com\/nursingpharmacology\/wp-json\/wp\/v2\/contributor?post=218"},{"taxonomy":"license","embeddable":true,"href":"https:\/\/pressbooks.publishdot.com\/nursingpharmacology\/wp-json\/wp\/v2\/license?post=218"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}