{"id":239,"date":"2019-11-14T21:00:37","date_gmt":"2019-11-14T21:00:37","guid":{"rendered":"https:\/\/pressbooks.publishdot.com\/nursingpharmacology\/chapter\/5-13-leukotriene-receptor-antagonists\/"},"modified":"2021-12-07T11:11:36","modified_gmt":"2021-12-07T11:11:36","slug":"5-13-leukotriene-receptor-antagonists","status":"publish","type":"chapter","link":"https:\/\/pressbooks.publishdot.com\/nursingpharmacology\/chapter\/5-13-leukotriene-receptor-antagonists\/","title":{"raw":"5.13 Leukotriene Receptor Antagonists","rendered":"5.13 Leukotriene Receptor Antagonists"},"content":{"raw":"Montelukast is a leukotriene antagonist medication with a distinctly shaped tablet. See Figure 5.18.[footnote]\"Singulair 10mg<\/a>\" by FedEx<\/a> is licenced under CC BY-NC-ND 2.0<\/a>[\/footnote]<\/sup>\n\nMechanism of Action<\/strong>\n\nMontelukast blocks leukotriene receptors and decreases inflammation.\n\nIndications for Use<\/strong>\n\nMontelukast is used for the long-term control of asthma and for decreasing the frequency of asthma attacks.\u00a0 It is also indicated for exercise-induced bronchospasm and allergic rhinitis.\n\nNursing Considerations Across the Lifespan<\/strong>\n\nThe medication is safe for children 12 months and older. It is available in granule packets and chewable tablets, as well as regular tablets.\n\nAdverse\/Side Effects<\/strong>\n\nMontelukast can cause headache, cough, nasal congestion, nausea, and hepatotoxicity.[footnote]Frandsen, G. & Pennington, S. (2018). Abrams\u2019 clinical drug: Rationales for nursing practice <\/em>(11th ed.). Wolters Kluwer.[\/footnote]<\/sup>\n\n[caption id=\"attachment_238\" align=\"aligncenter\" width=\"433\"]\"Photo Figure 5.18 Montelukast Tablets[\/caption]\n\nPatient Teaching & Education<\/strong>\n\nPatients should be instructed to take medications at the same time each day and at least two hours prior to exercise.\u00a0 They should not discontinue medications without notifying the healthcare provider.[footnote]uCentral from Unbound Medicine. https:\/\/www.unboundmedicine.com\/ucentral<\/a>[\/footnote]<\/sup>\n\nNow let's take a closer look at the medication grid on montelukast in Table 5.13.[footnote]This work is a derivative of Pharmacology Notes: Nursing Implications for Clinical Practice<\/a> by Gloria Velarde<\/a> licensed under CC BY-NC-SA 4.0<\/a>.[\/footnote],[footnote]Frandsen, G. & Pennington, S. (2018). Abrams\u2019 clinical drug: Rationales for nursing practice <\/em>(11th ed.). Wolters Kluwer.[\/footnote], [footnote]This work is a derivative of Daily Med<\/a> by U.S. National Library of Medicine<\/a> in the public domain<\/a>. [\/footnote],[footnote]Adams, M., Holland, N., & Urban, C. (2020). Pharmacology for nurses: A pathophysiologic approach <\/em>(6th ed.).<\/em> pp. 622-63 & 626. Pearson. [\/footnote]<\/sup>\n\nTable 5.13 Montelukast Medication Grid\n\n\n\n\n
\n
Class\/Subclass<\/strong><\/h5>\n<\/th>\n
\n
Prototype\/Generic<\/strong><\/h5>\n<\/th>\n
\n
Administration Considerations<\/strong><\/h5>\n<\/th>\n
\n
Therapeutic Effects<\/strong><\/h5>\n<\/th>\n
\n
Adverse\/Side Effects<\/strong><\/h5>\n<\/th>\n<\/tr>\n
Leukotriene inhibitor<\/th>\nmontelukast<\/a><\/td>\nUse as directed; not to be used as \"rescue\" medication\n\nTypically 3-7 days to reach effectiveness<\/td>\nPrevention and treatment of asthma and exercise-induced bronchoconstriction<\/td>\nHeadache\n\nCough\n\nNasal congestion\n\nNausea\n\nHepatotoxicity<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n ","rendered":"

Montelukast is a leukotriene antagonist medication with a distinctly shaped tablet. See Figure 5.18.[1]<\/sup><\/a><\/sup><\/p>\n

Mechanism of Action<\/strong><\/p>\n

Montelukast blocks leukotriene receptors and decreases inflammation.<\/p>\n

Indications for Use<\/strong><\/p>\n

Montelukast is used for the long-term control of asthma and for decreasing the frequency of asthma attacks.\u00a0 It is also indicated for exercise-induced bronchospasm and allergic rhinitis.<\/p>\n

Nursing Considerations Across the Lifespan<\/strong><\/p>\n

The medication is safe for children 12 months and older. It is available in granule packets and chewable tablets, as well as regular tablets.<\/p>\n

Adverse\/Side Effects<\/strong><\/p>\n

Montelukast can cause headache, cough, nasal congestion, nausea, and hepatotoxicity.[2]<\/sup><\/a><\/sup><\/p>\n

\"Photo
Figure 5.18 Montelukast Tablets<\/figcaption><\/figure>\n

Patient Teaching & Education<\/strong><\/p>\n

Patients should be instructed to take medications at the same time each day and at least two hours prior to exercise.\u00a0 They should not discontinue medications without notifying the healthcare provider.[3]<\/sup><\/a><\/sup><\/p>\n

Now let’s take a closer look at the medication grid on montelukast in Table 5.13.[4]<\/sup><\/a>,[5]<\/sup><\/a>, [6]<\/sup><\/a>,[7]<\/sup><\/a><\/sup><\/p>\n

Table 5.13 Montelukast Medication Grid<\/p>\n\n\n\n\n
\n
Class\/Subclass<\/strong><\/h5>\n<\/th>\n
\n
Prototype\/Generic<\/strong><\/h5>\n<\/th>\n
\n
Administration Considerations<\/strong><\/h5>\n<\/th>\n
\n
Therapeutic Effects<\/strong><\/h5>\n<\/th>\n
\n
Adverse\/Side Effects<\/strong><\/h5>\n<\/th>\n<\/tr>\n
Leukotriene inhibitor<\/th>\nmontelukast<\/a><\/td>\nUse as directed; not to be used as “rescue” medication<\/p>\n

Typically 3-7 days to reach effectiveness<\/td>\n

Prevention and treatment of asthma and exercise-induced bronchoconstriction<\/td>\nHeadache<\/p>\n

Cough<\/p>\n

Nasal congestion<\/p>\n

Nausea<\/p>\n

Hepatotoxicity<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n

  1. \"Singulair 10mg<\/a>\" by FedEx<\/a> is licenced under CC BY-NC-ND 2.0<\/a> ↵<\/a><\/li>
  2. Frandsen, G. & Pennington, S. (2018). Abrams\u2019 clinical drug: Rationales for nursing practice <\/em>(11th ed.). Wolters Kluwer. ↵<\/a><\/li>
  3. uCentral from Unbound Medicine. https:\/\/www.unboundmedicine.com\/ucentral<\/a> ↵<\/a><\/li>
  4. This work is a derivative of Pharmacology Notes: Nursing Implications for Clinical Practice<\/a> by Gloria Velarde<\/a> licensed under CC BY-NC-SA 4.0<\/a>. ↵<\/a><\/li>
  5. Frandsen, G. & Pennington, S. (2018). Abrams\u2019 clinical drug: Rationales for nursing practice <\/em>(11th ed.). Wolters Kluwer. ↵<\/a><\/li>
  6. This work is a derivative of Daily Med<\/a> by U.S. National Library of Medicine<\/a> in the public domain<\/a>. ↵<\/a><\/li>
  7. Adams, M., Holland, N., & Urban, C. (2020). Pharmacology for nurses: A pathophysiologic approach <\/em>(6th ed.).<\/em> pp. 622-63 & 626. Pearson. ↵<\/a><\/li><\/ol><\/div>","protected":false},"author":2,"menu_order":13,"template":"","meta":{"pb_show_title":"on","pb_short_title":"","pb_subtitle":"","pb_authors":[],"pb_section_license":"cc-by"},"chapter-type":[49],"contributor":[],"license":[53],"class_list":["post-239","chapter","type-chapter","status-publish","hentry","chapter-type-numberless","license-cc-by"],"part":195,"_links":{"self":[{"href":"https:\/\/pressbooks.publishdot.com\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapters\/239","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pressbooks.publishdot.com\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapters"}],"about":[{"href":"https:\/\/pressbooks.publishdot.com\/nursingpharmacology\/wp-json\/wp\/v2\/types\/chapter"}],"author":[{"embeddable":true,"href":"https:\/\/pressbooks.publishdot.com\/nursingpharmacology\/wp-json\/wp\/v2\/users\/2"}],"version-history":[{"count":1,"href":"https:\/\/pressbooks.publishdot.com\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapters\/239\/revisions"}],"predecessor-version":[{"id":240,"href":"https:\/\/pressbooks.publishdot.com\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapters\/239\/revisions\/240"}],"part":[{"href":"https:\/\/pressbooks.publishdot.com\/nursingpharmacology\/wp-json\/pressbooks\/v2\/parts\/195"}],"metadata":[{"href":"https:\/\/pressbooks.publishdot.com\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapters\/239\/metadata\/"}],"wp:attachment":[{"href":"https:\/\/pressbooks.publishdot.com\/nursingpharmacology\/wp-json\/wp\/v2\/media?parent=239"}],"wp:term":[{"taxonomy":"chapter-type","embeddable":true,"href":"https:\/\/pressbooks.publishdot.com\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapter-type?post=239"},{"taxonomy":"contributor","embeddable":true,"href":"https:\/\/pressbooks.publishdot.com\/nursingpharmacology\/wp-json\/wp\/v2\/contributor?post=239"},{"taxonomy":"license","embeddable":true,"href":"https:\/\/pressbooks.publishdot.com\/nursingpharmacology\/wp-json\/wp\/v2\/license?post=239"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}